Novel pre-vascularized tissue-engineered dermis based on stem cell sheet technique used for dermis-defect healing

Dermis isolated adult stem cells for cartilage tissue engineering.

Adult stem cells from the dermal layer of skin are an attractive alternative to primary cells for meniscus engineering, as they may be easily obtained and used autologously. Recently, chondroinducible dermis cells from caprine skin have shown promising characteristics for cartilage tissue engineering. In this study, their multilineage differentiation capacity is determined, and methods of expan...

Investigation of Dermis-derived hydrogels for wound healing applications.

BACKGROUND Wound healing and skin tissue engineering are mediated, in part, by interactions between cells and the extracellular matrix (ECM). A subset of the ECM, basement membranes (BM), plays a vital role in regulating proper skin healing and function. METHODS ECM-rich, tissue-specific hydrogels were extracted and assembled from dermis samples. These hydrogels contain BM proteins vital to s...

Suitability of Dermis versus Adipose Tissue as Adult Stem Cell Source in One-step Surgical Procedure for Cartilage Tissue Engineering

The ability of stem cells to self-renew as well as their multilineage differentiation potential makes them ideal candidates for skin regeneration strategies. Mesenchymal stem cells residing in human adult dermis, in contrast to adipose tissue, have not yet been described. The objective of this study was to determine the stemness and chemokine-mediated homing potential of dermal stromal cells (D...

Results of Acellular Dermis Matrix Graft Used for Tympanoplasty in Guinea Pig Model

Introduction: To describe the underlay tympanoplasty technique using an acellular dermal graft(AlloDerm) for tympanic membrane (TM) reconstruction in a guinea pig model and to demonstrate the feasibility of the technique using AlloDerm tissue harvested from the prepuce as a source of tissue for future grafting in human TM reconstruction.   Materials and Methods: The prepuce was divided during c...

Plasma cell leukaemia relapsing in the dermis.